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Studies have demonstrated that metformin administration can enhance the autophagy, proliferation, and promote differentiation in granulosa cells while suppressing apoptotic pathways

For catalase and peroxidase, the evidence indicates that hydrogen peroxide binds to the ferric center and then undergoes heterolysis at the OO bond

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Conclusion We conclude that addition of ALC therapy is superior to metformin plus pioglitazone in ameliorating insulin resistance, polycystic ovaries, menstrual irregularities, and hypoadiponectinemia in women with PCOS